BDBM50047420 CHEMBL3319405

SMILES CN1CCC(CC1)S(=O)(=O)c1ccc2nc(NC(=O)NC(=O)c3cc(ccc3Cl)N3CCOCC3)sc2c1

InChI Key InChIKey=XEOOLDLJXYEALJ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50047420   

TargetGrowth hormone secretagogue receptor type 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50047420(CHEMBL3319405)
Affinity DataIC50: 0.770nMAssay Description:Inverse agonist activity at GHS-R1a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50047420(CHEMBL3319405)
Affinity DataIC50: 6.70nMAssay Description:Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
LigandPNGBDBM50047420(CHEMBL3319405)
Affinity DataKi:  52nMAssay Description:Inhibition of alpha4 nAChR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047420(CHEMBL3319405)
Affinity DataKi:  290nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed