BDBM50047557 1-Butyl-3-{2-[3-(5-ethyl-4-phenyl-imidazol-1-yl)-propoxy]-6-methyl-phenyl}-urea::CHEMBL47095

SMILES CCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1CC)-c1ccccc1

InChI Key InChIKey=NQZTZGNLFLQHKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50047557   

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047557(1-Butyl-3-{2-[3-(5-ethyl-4-phenyl-imidazol-1-yl)-p...)
Affinity DataIC50: 88nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetyl-CoA acetyltransferase, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50047557(1-Butyl-3-{2-[3-(5-ethyl-4-phenyl-imidazol-1-yl)-p...)
Affinity DataIC50: 97nMAssay Description:Inhibition of ACAT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047557(1-Butyl-3-{2-[3-(5-ethyl-4-phenyl-imidazol-1-yl)-p...)
Affinity DataIC50: 160nMAssay Description:Tested for inhibition against Acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate (>, denotes no effect at the concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed