BDBM50048001 4-Methyl-5-[2-(3-trifluoromethyl-phenylamino)-phenyl]-4H-[1,2,4]triazole-3-thiol::CHEMBL298776

SMILES Cn1c(-c2ccccc2Nc2cccc(C(F)(F)F)c2)n[nH]c1=S

InChI Key InChIKey=OTVUMULVNMAVEX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50048001   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048001BDBM50048001(4-Methyl-5-[2-(3-trifluoromethyl-phenylamino)-phen...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048001BDBM50048001(4-Methyl-5-[2-(3-trifluoromethyl-phenylamino)-phen...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed