BDBM50048501 CHEMBL146823::[(3S,7R)-7-Cyclopropylmethyl-3-((S)-2-mercapto-3-phenyl-propionylamino)-2-oxo-azepan-1-yl]-acetic acid

SMILES OC(=O)CN1[C@@H](CC2CC2)CCC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O

InChI Key InChIKey=VEDUWGNJXRLFHV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50048501   

TargetAngiotensin-converting enzyme(Rabbit)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50048501([(3S,7R)-7-Cyclopropylmethyl-3-((S)-2-mercapto-3-p...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme isolated from rabbit lung extract.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50048501([(3S,7R)-7-Cyclopropylmethyl-3-((S)-2-mercapto-3-p...)
Affinity DataIC50: 140nMAssay Description:In vitro inhibition of purified rat kidney Neutral endopeptidase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed