BDBM50048582 (5-Bromo-indol-1-yl)-propyl-pyridin-4-yl-amine::CHEMBL347914

SMILES CCCN(c1ccncc1)n1ccc2cc(Br)ccc12

InChI Key InChIKey=ZGKKKWMQYVOFGE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50048582   

TargetSodium-dependent noradrenaline transporter(Human)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048582((5-Bromo-indol-1-yl)-propyl-pyridin-4-yl-amine | C...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory activity against norepinephrine (NE) uptake in rat whole brain synaptosome preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048582((5-Bromo-indol-1-yl)-propyl-pyridin-4-yl-amine | C...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of [3H]quinuclidinyl benzilate (QNB) binding from rat forebrain membranes in the absence of ZnMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048582((5-Bromo-indol-1-yl)-propyl-pyridin-4-yl-amine | C...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of [3H]quinuclidinyl benzilate (QNB) binding from rat forebrain membranes in the presence of ZnMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048582((5-Bromo-indol-1-yl)-propyl-pyridin-4-yl-amine | C...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against acetylcholinesterase in rat striatal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed