BDBM50048610 CHEMBL435034::Carbazol-9-yl-propyl-pyridin-4-yl-amine; compound with (E)-but-2-enedioic acid

SMILES CCCN(c1ccncc1)n1c2ccccc2c2ccccc12

InChI Key InChIKey=OEWRTGUPTVTVPH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50048610   

TargetSodium-dependent noradrenaline transporter(Human)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048610(CHEMBL435034 | Carbazol-9-yl-propyl-pyridin-4-yl-a...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity against norepinephrine (NE) uptake in rat whole brain synaptosome preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048610(CHEMBL435034 | Carbazol-9-yl-propyl-pyridin-4-yl-a...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against acetylcholinesterase in rat striatal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048610(CHEMBL435034 | Carbazol-9-yl-propyl-pyridin-4-yl-a...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of [3H]quinuclidinyl benzilate (QNB) binding from rat forebrain membranes in the absence of ZnMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048610(CHEMBL435034 | Carbazol-9-yl-propyl-pyridin-4-yl-a...)
Affinity DataIC50:  500nMAssay Description:Inhibition of [3H]quinuclidinyl benzilate (QNB) binding from rat forebrain membranes in the presence of ZnMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50048610(CHEMBL435034 | Carbazol-9-yl-propyl-pyridin-4-yl-a...)
Affinity DataIC50:  540nMAssay Description:Inhibitory activity against [3H]clonidine binding to Alpha-2 adrenergic receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048610(CHEMBL435034 | Carbazol-9-yl-propyl-pyridin-4-yl-a...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory activity against [3H]WB-4101 binding to Alpha-1 adrenergic receptor in rat whole brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed