BDBM50049036 5-(3-Chloro-4-methoxy-phenyl)-6-(4-methanesulfonyl-phenyl)-spiro[2.4]hepta-4,6-diene::CHEMBL89625

SMILES COc1ccc(cc1Cl)C1=CC2(CC2)C=C1c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=WLFJJROWUATIOC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049036   

TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50049036(5-(3-Chloro-4-methoxy-phenyl)-6-(4-methanesulfonyl...)
Affinity DataIC50: 26.9nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50049036(5-(3-Chloro-4-methoxy-phenyl)-6-(4-methanesulfonyl...)
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049036(5-(3-Chloro-4-methoxy-phenyl)-6-(4-methanesulfonyl...)
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed