BDBM50049040 4-[6-(3-Bromo-4-methoxy-phenyl)-spiro[2.4]hept-5-en-5-yl]-benzenesulfonamide::CHEMBL313313

SMILES COc1ccc(cc1Br)C1=C(CC2(CC2)C1)c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=QJSBOZBRPNQYEP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049040   

TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049040(4-[6-(3-Bromo-4-methoxy-phenyl)-spiro[2.4]hept-5-e...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50049040(4-[6-(3-Bromo-4-methoxy-phenyl)-spiro[2.4]hept-5-e...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50049040(4-[6-(3-Bromo-4-methoxy-phenyl)-spiro[2.4]hept-5-e...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity of the compound against prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed