BDBM50049283 2-Fluoro-4-{[7-methyl-4-oxo-2-(pyrimidin-2-ylsulfanylmethyl)-3,4-dihydro-quinazolin-6-ylmethyl]-prop-2-ynyl-amino}-N-(3-nitro-benzyl)-benzamide::CHEMBL159591

SMILES C#CCN(Cc1cc2c(=O)[nH]c(CSc3ncccn3)nc2cc1C)c1ccc(C(=O)NCc2cccc([N+](=O)[O-])c2)c(F)c1

InChI Key InChIKey=SEGRUFWVRLIDNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049283   

TargetThymidylate synthase(Mouse)
Zeneca Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049283BDBM50049283(2-Fluoro-4-{[7-methyl-4-oxo-2-(pyrimidin-2-ylsulfa...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed