BDBM50049286 2-{4-[(2-Aminomethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-succinic acid::CHEMBL159593

SMILES C#CCN(Cc1ccc2nc(CN)[nH]c(=O)c2c1)c1ccc(C(=O)NC(CC(=O)O)C(=O)O)cc1

InChI Key InChIKey=ZCVQMPIMFWGGRD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049286   

TargetThymidylate synthase(Mouse)
Zeneca Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049286BDBM50049286(2-{4-[(2-Aminomethyl-4-oxo-3,4-dihydro-quinazolin-...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed