BDBM50049398 3,5,7-Trimethoxy-2-(4-methoxy-phenyl)-chromen-4-one::CHEMBL356036

SMILES COc1ccc(cc1)-c1oc2cc(OC)cc(OC)c2c(=O)c1OC

InChI Key InChIKey=YZWIIEJLESXODL-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50049398   

TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50049398(3,5,7-Trimethoxy-2-(4-methoxy-phenyl)-chromen-4-on...)
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of specific [3H]PIA binding from adenosine A1 receptor in rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50049398(3,5,7-Trimethoxy-2-(4-methoxy-phenyl)-chromen-4-on...)
Affinity DataKi:  1.07E+3nMAssay Description:Ability to displace [3H]N6-phenylisopropyladenosine binding from adenosine A1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50049398(3,5,7-Trimethoxy-2-(4-methoxy-phenyl)-chromen-4-on...)
Affinity DataKi:  3.37E+3nMAssay Description:Displacement of [125I]AB-MECA binding to human Adenosine A3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50049398(3,5,7-Trimethoxy-2-(4-methoxy-phenyl)-chromen-4-on...)
Affinity DataKi:  3.39E+3nMAssay Description:Ability to displace [125I]-AB-MECA binding from adenosine A3 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Human)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50049398(3,5,7-Trimethoxy-2-(4-methoxy-phenyl)-chromen-4-on...)
Affinity DataIC50: 3.95E+4nMAssay Description:Inhibition of OCT2(unknown origin)-mediated ASP+ uptake in HEK293 cells expressing OCT2 using ASP+ as substrate incubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 1(Human)
Tianjin University

Curated by ChEMBL
LigandPNGBDBM50049398(3,5,7-Trimethoxy-2-(4-methoxy-phenyl)-chromen-4-on...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of OCT1(unknown origin)-mediated ASP+ uptake in HEK293 cells expressing OCT1 using ASP+ as substrate incubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed