BDBM50049595 6-(Naphthalen-1-ylsulfanylmethyl)-pyrido[3,2-d]pyrimidine-2,4-diamine::CHEMBL55656

SMILES Nc1nc(N)c2nc(CSc3cccc4ccccc34)ccc2n1

InChI Key InChIKey=KUKKYMVHCDIMNT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50049595   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049595(6-(Naphthalen-1-ylsulfanylmethyl)-pyrido[3,2-d]pyr...)
Affinity DataIC50: 49nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049595(6-(Naphthalen-1-ylsulfanylmethyl)-pyrido[3,2-d]pyr...)
Affinity DataIC50: 49nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049595(6-(Naphthalen-1-ylsulfanylmethyl)-pyrido[3,2-d]pyr...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049595(6-(Naphthalen-1-ylsulfanylmethyl)-pyrido[3,2-d]pyr...)
Affinity DataIC50: 160nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Baker's yeast)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049595(6-(Naphthalen-1-ylsulfanylmethyl)-pyrido[3,2-d]pyr...)
Affinity DataIC50: 470nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049595(6-(Naphthalen-1-ylsulfanylmethyl)-pyrido[3,2-d]pyr...)
Affinity DataIC50: 470nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed