BDBM50050473 1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-piperidine::1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-2H-pyrazol-3-yl]-piperidine::CHEMBL61080

SMILES Clc1ccc(CN2CCC(CC2)c2cc(n[nH]2)-c2ccc(Cl)cc2)cc1

InChI Key InChIKey=YATPAHDOUJPRNV-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50050473   

TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050473(1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyra...)
Affinity DataKi:  61nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D4 (hD4) receptor stably expressed in HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050473(1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyra...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050473(1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyra...)
Affinity DataKi:  61nMAssay Description:Binding affinity towards human dopamine receptor D4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050473(1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyra...)
Affinity DataKi:  240nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D2 stably expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050473(1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyra...)
Affinity DataKi:  240nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050473(1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyra...)
Affinity DataKi:  820nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D3 (hD3) receptor stably expressed in HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050473(1-(4-Chloro-benzyl)-4-[5-(4-chloro-phenyl)-1H-pyra...)
Affinity DataKi:  820nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed