BDBM50051166 1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrrolidine-2,5-dione::1-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-pyrrolidine-2,5-dione::CHEMBL279841

SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CCC2=O)CC1

InChI Key InChIKey=MQHOGPLXAXSQAJ-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50051166   

Target5-hydroxytryptamine receptor 1A(Rat)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50051166(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrr...)
Affinity DataKi:  6.40nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in the rat brain (hippocampus) using [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Rat)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50051166(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrr...)
Affinity DataKi:  6.40nMAssay Description:In vitro ability to displace the radioligand [3H]-OH-DPAT from binding to rat 5-hydroxytryptamine 1A receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Rat)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50051166(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrr...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]8-OH-DPAT from serotonin 5HT1A receptor in rat brain hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Cracow University of Technology

Curated by ChEMBL
LigandPNGBDBM50051166(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrr...)
Affinity DataKi:  6.40nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50051166(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrr...)
Affinity DataKi:  12nMAssay Description:Alpha-1 adrenergic receptor binding affinity of the compound, value taken from literatureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Rat)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50051166(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrr...)
Affinity DataKi:  90nMAssay Description:In vitro ability to displace the radioligand [3H]-5-CT from binding to rat 5-hydroxytryptamine 7 receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Cracow University of Technology

Curated by ChEMBL
LigandPNGBDBM50051166(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrr...)
Affinity DataKi:  90nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed

TargetD(2) dopamine receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50051166(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrr...)
Affinity DataKi:  490nMAssay Description:Displacement of [3H]spiperone from dopaminergic D2 receptor in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50051166(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrr...)
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of [3H]ketanserin from serotonin 5HT2A receptor in rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed