BDBM50051206 (4-Trifluoromethyl-phenyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester::CHEMBL16565

SMILES O=C(Nc1ccc(C(F)(F)F)cc1)OCCCc1cnc[nH]1

InChI Key InChIKey=VVGXIYVZJGKQDO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50051206   

TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051206BDBM50051206((4-Trifluoromethyl-phenyl)-carbamic acid 3-(1H-imi...)
Affinity DataKi:  15nMAssay Description:In vitro antagonistic activity against Histamine H3 receptor on Synaptosomes of rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051206BDBM50051206((4-Trifluoromethyl-phenyl)-carbamic acid 3-(1H-imi...)
Affinity DataKi:  15.8nMAssay Description:Binding affinity against Histamine H3 receptor on Synaptosomes from rat cerebral cortex was evaluatedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051206BDBM50051206((4-Trifluoromethyl-phenyl)-carbamic acid 3-(1H-imi...)
Affinity DataKi:  1.58E+4nMAssay Description:Binding affinity against H1 receptor of Guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Guinea pig)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051206BDBM50051206((4-Trifluoromethyl-phenyl)-carbamic acid 3-(1H-imi...)
Affinity DataKi:  3.98E+4nMAssay Description:Binding affinity against H2 receptor of Guinea pig atriumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed