BDBM50051250 CHEMBL545144::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3-bromo-2,6-dimethoxy-benzamide; hydrochloride

SMILES COc1ccc(Br)c(OC)c1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12

InChI Key InChIKey=RHAFVVVYTKSXMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50051250   

TargetD(2) dopamine receptor(Rat)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50051250(N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory activity against [3H]raclopride binding to dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50051250(N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 74nMAssay Description:In vitro inhibitory activity against [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed