BDBM50051251 CHEMBL542058::{2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butylcarbamoyl]-phenyl}-carbamic acid ethyl ester; hydrochloride

SMILES CCOC(=O)Nc1ccccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12

InChI Key InChIKey=LOGBZPHGQPXCHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50051251   

TargetD(2) dopamine receptor(Rat)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50051251({2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-b...)
Affinity DataIC50: 5.40nMAssay Description:In vitro inhibitory activity against [3H]raclopride binding to dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50051251({2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-b...)
Affinity DataIC50: 5.60nMAssay Description:In vitro inhibitory activity against [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed