BDBM50051822 CHEMBL284424::[(S)-4-((R)-2-Amino-3-mercapto-propyl)-3-ethyl-piperazin-1-yl]-(2,3-dimethyl-phenyl)-methanone

SMILES CC[C@H]1CN(CCN1C[C@@H](N)CS)C(=O)c1cccc(C)c1C

InChI Key InChIKey=QHEJXFYXXWVDRL-CVEARBPZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051822   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051822(CHEMBL284424 | [(S)-4-((R)-2-Amino-3-mercapto-prop...)
Affinity DataIC50:  68nMAssay Description:Inhibition of [3H]-FPP incorporation into Ha-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed