BDBM50051824 CHEMBL283208::[(S)-4-((R)-2-Amino-3-mercapto-propyl)-3-butyl-piperazin-1-yl]-(2,3-dimethyl-phenyl)-methanone
SMILES CCCC[C@H]1CN(CCN1C[C@@H](N)CS)C(=O)c1cccc(C)c1C
InChI Key InChIKey=IWQXXMWFEZGUPJ-MSOLQXFVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50051824
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]-FPP incorporation into Ha-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Bovine)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of bovine Geranylgeranyl transferase type IMore data for this Ligand-Target Pair