BDBM50051886 CHEMBL289465::[2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[1,3]dioxan-5-yl]-methanol

SMILES CC1(CO)COC(OC1)c1nc(c([nH]1)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=WTRKWLHEIVJAHM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50051886   

TargetSterol O-acyltransferase 1(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051886([2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[1,3]d...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051886([2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[1,3]d...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051886([2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[1,3]d...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibitory concentration was evaluated as concentration required to inhibit 50% activity of the rabbit liver Acyl coenzyme A:cholesterol acyltransfer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051886([2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[1,3]d...)
Affinity DataIC50: 4.45E+3nMAssay Description:Inhibitory concentration was evaluated as concentration required to inhibit 50% activity of the rabbit artery Acyl coenzyme A:cholesterol acyltransfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed