BDBM50052357 3-Biphenyl-4-ylmethyl-1-aza-bicyclo[2.2.2]octane::3-[1'-(Biphenyl)-methyl]-quinuclidine::CHEMBL99679

SMILES c1ccc(-c2ccc(CC3CN4CCC3CC4)cc2)cc1

InChI Key InChIKey=QBLZXWRXSWVMCP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052357   

TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052357BDBM50052357(3-Biphenyl-4-ylmethyl-1-aza-bicyclo[2.2.2]octane |...)
Affinity DataIC50: 27nMAssay Description:In vitro inhibition against rat microsomal squalene synthase (SS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052357BDBM50052357(3-Biphenyl-4-ylmethyl-1-aza-bicyclo[2.2.2]octane |...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed