BDBM50052617 3-(3,5-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionamide::CHEMBL419204

SMILES COc1cc(OC)cc(c1)C(CC(N)=O)N1C(=O)c2ccccc2C1=O

InChI Key InChIKey=KPCSISQFPQWXTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052617   

TargetTumor necrosis factor(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50052617(3-(3,5-Dimethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of TNF-alpha production in LPS stimulated human PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed