BDBM50052910 CHEMBL118271::N-[4-(5-Hydroxy-2,3,4,5-tetrahydro-benzo[b]azepine-1-carbonyl)-phenyl]-2-methyl-benzamide

SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCC(O)c2ccccc12

InChI Key InChIKey=QDPVGLNUJIYJDL-UHFFFAOYSA-N

Data  2 KI  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50052910   

TargetVasopressin V1a receptor(Human)
Teikyo University

Curated by ChEMBL

LigandBDBM50052910(CHEMBL118271 | N-[4-(5-Hydroxy-2,3,4,5-tetrahydro-...)Copy SMILESCopy InChI

Affinity DataKi:  1.60nMAssay Description:Displacement of [125I] phenylacetyl-D-Tyr(Me)-Phe-Gln-Asn-Arg-Pro-Arg-Tyr-NH2 from human recombinant vasopressin V1a receptor expressed in HEK293 aft...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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TargetVasopressin V2 receptor(Human)
Teikyo University

Curated by ChEMBL

LigandBDBM50052910(CHEMBL118271 | N-[4-(5-Hydroxy-2,3,4,5-tetrahydro-...)Copy SMILESCopy InChI

Affinity DataKi:  7.60nMAssay Description:Displacement of [3H] (Arg8)-vasopressin from human vasopressin V2 receptor expressed in CHOK1 cell membranes after 2 hrs by liquid scintillation coun...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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TargetVasopressin V2 receptor(Rat)
Otsuka Pharmaceutical

Curated by ChEMBL

LigandBDBM50052910(CHEMBL118271 | N-[4-(5-Hydroxy-2,3,4,5-tetrahydro-...)Copy SMILESCopy InChI

Affinity DataIC50:  29nMAssay Description:Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidneyMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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TargetVasopressin V1a receptor(Rat)
Otsuka Pharmaceutical

Curated by ChEMBL

LigandBDBM50052910(CHEMBL118271 | N-[4-(5-Hydroxy-2,3,4,5-tetrahydro-...)Copy SMILESCopy InChI

Affinity DataIC50:  140nMAssay Description:Displacement of [3H]-AVP from AVP-V1a receptor binding site in rat liverMore data for this Ligand-Target Pair

Target InfoReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL