BDBM50053106 CHEMBL120112::[1-Aminooxalyl-2-ethyl-3-(3-trifluoromethyl-benzyl)-indolizin-8-yloxy]-acetic acid

SMILES CCc1c(Cc2cccc(c2)C(F)(F)F)n2cccc(OCC(O)=O)c2c1C(=O)C(N)=O

InChI Key InChIKey=NJPROSWBIXBLCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053106   

TargetPhospholipase A2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053106([1-Aminooxalyl-2-ethyl-3-(3-trifluoromethyl-benzyl...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053106([1-Aminooxalyl-2-ethyl-3-(3-trifluoromethyl-benzyl...)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed