BDBM50054067 (2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-ammonium(R(+)7OH-DPAT)::(R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol.HCl::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL301559

SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1

InChI Key InChIKey=BLYMJBIZMIGWFK-OAHLLOKOSA-N

Data  20 KI  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50054067   

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  0.5nMAssay Description:Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article

TargetD(3) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  0.570nMAssay Description:In vitro binding affinity at human Dopamine receptor D3 expressed in CHO K1 cells was measured by its ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  0.570nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  0.600nMAssay Description:Ability to displace radioligand [3H]spiperone from human dopamine D3 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair
In DepthDetails Article

TargetD(3) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  2.35nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  2.35nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  5nMAssay Description:In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  8nMAssay Description:In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  8nMAssay Description:In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  34nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]N-0437 binding on Dopamine receptor D2L of CHO K-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  34nMAssay Description:In vitro binding affinity at human Dopamine receptor D2 expressed in CHO K1 cells was measured by its ability to displace [3H]- N-0437More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]spiperone from human D2S receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  56nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D2L of CHO K-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(4) dopamine receptor(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  110nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D4.2 of CHO K-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  202nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  202nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Rat)
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  340nMAssay Description:Binding affinity against dopamine receptor D2 in rat brain tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Rat)
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  3.26E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in homogenated rat brain tissue, using by [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-2 adrenergic receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKi:  8.60E+4nMAssay Description:Displacement of [3H]CGP12177 from human beta2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Rat)
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKd:  1.10E+3nMAssay Description:In vitro affinity at mutant D2 receptor (S193A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Rat)
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKd:  300nMAssay Description:In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Rat)
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKd:  400nMAssay Description:In vitro affinity at wild type Dopamine receptor D2 on C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Rat)
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50054067((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...)
Affinity DataKd:  1.00E+3nMAssay Description:In vitro affinity at mutant D2 receptor (S197A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed