BDBM50054508 2-Amino-6-methyl-5-(naphthalen-2-ylsulfanyl)-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL141118

SMILES Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc2ccccc2c1

InChI Key InChIKey=HOUIERONDBLBSH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054508   

TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054508(2-Amino-6-methyl-5-(naphthalen-2-ylsulfanyl)-3,7-d...)
Affinity DataIC50: 2.00E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054508(2-Amino-6-methyl-5-(naphthalen-2-ylsulfanyl)-3,7-d...)
Affinity DataIC50: 2.50E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Streptococcus faecium Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054508(2-Amino-6-methyl-5-(naphthalen-2-ylsulfanyl)-3,7-d...)
Affinity DataIC50: 2.50E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054508(2-Amino-6-methyl-5-(naphthalen-2-ylsulfanyl)-3,7-d...)
Affinity DataIC50: 2.50E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed