BDBM50054554 (Z)-N-[4-(4-Chloro-benzoyl)-phenyl]-2-cyano-3-cyclopropyl-3-hydroxy-acrylamide::CHEMBL143196

SMILES Clc1ccc(cc1)C(=O)c1ccc(NC(=O)C(C#N)C(=O)C2CC2)cc1

InChI Key InChIKey=VMPYCTXJHYSIRH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054554   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mouse)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054554((Z)-N-[4-(4-Chloro-benzoyl)-phenyl]-2-cyano-3-cycl...)
Affinity DataIC50: 562nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054554((Z)-N-[4-(4-Chloro-benzoyl)-phenyl]-2-cyano-3-cycl...)
Affinity DataIC50: 590nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed