BDBM50054664 2-Methyl-6-(4-nitro-phenyl)-4-((E)-styryl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester::CHEMBL140693

SMILES CCOC(=[OH+])C1=C(C)N=C(c2ccc([N+](=O)[O-])cc2)/C(=C(/[O-])OCC)C1/C=C/c1ccccc1

InChI Key InChIKey=OOXUYGQRUGHTMH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054664   

TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054664BDBM50054664(2-Methyl-6-(4-nitro-phenyl)-4-((E)-styryl)-1,4-dih...)
Affinity DataKi:  4.14E+3nMAssay Description:Binding affinity against cloned human adenosine A3 receptor by radioligand binding assay using [125I]-AB-MECA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054664BDBM50054664(2-Methyl-6-(4-nitro-phenyl)-4-((E)-styryl)-1,4-dih...)
Affinity DataKi:  1.31E+4nMAssay Description:Binding affinity against adenosine A1 receptor in rat cerebral cortex membrane by radioligand binding assay using [3H](R)-PIA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054664BDBM50054664(2-Methyl-6-(4-nitro-phenyl)-4-((E)-styryl)-1,4-dih...)
Affinity DataKi:  4.00E+4nMAssay Description:Displacement of [3H]-CGS- 21680 from Adenosine A2A receptor of rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed