BDBM50054989 1-[2-(7-Methoxy-3,4-dihydro-naphthalen-2-yl)-ethyl]-4-phenyl-piperazine::CHEMBL342518

SMILES COc1ccc2CCC(CCN3CCN(CC3)c3ccccc3)=Cc2c1

InChI Key InChIKey=HMRKDGYERNRWGG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054989   

Target5-hydroxytryptamine receptor 1A(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50054989(1-[2-(7-Methoxy-3,4-dihydro-naphthalen-2-yl)-ethyl...)
Affinity DataIC50: 7.30nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 1A receptor was evaluated using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50054989(1-[2-(7-Methoxy-3,4-dihydro-naphthalen-2-yl)-ethyl...)
Affinity DataIC50: 106nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 2A receptor was evaluated using [3H]- ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50054989(1-[2-(7-Methoxy-3,4-dihydro-naphthalen-2-yl)-ethyl...)
Affinity DataIC50: 136nMAssay Description:Binding affinity towards rat Dopamine receptor D2 was evaluated using [3H]- spiroperidol as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed