BDBM50055622 CHEMBL386619::[(R)-1-((R)-2-(4-Benzyloxy-phenyl)-1-{(R)-1-[(R)-1-((S)-1-carbamoyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-phosphonooxy-ethylcarbamoyl}-ethylcarbamoyl)-2-(1H-imidazol-4-yl)-ethyl]-carbamic acid benzyl ester

SMILES C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](COP(O)(O)=O)NC(=O)[C@@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)C(N)=O

InChI Key InChIKey=JAHDKNXLWYZKQE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50055622   

LigandPNGBDBM50055622([(R)-1-((R)-2-(4-Benzyloxy-phenyl)-1-{(R)-1-[(R)-1...)
Affinity DataIC50: 240nMAssay Description:Inhibition of rat brain farnesyltransferase in 30 mM potassium phosphate bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50055622([(R)-1-((R)-2-(4-Benzyloxy-phenyl)-1-{(R)-1-[(R)-1...)
Affinity DataIC50: 360nMAssay Description:Inhibition of rat brain farnesyltransferase in 5 mM potassium phosphate and 50 mM HEPES bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50055622([(R)-1-((R)-2-(4-Benzyloxy-phenyl)-1-{(R)-1-[(R)-1...)
Affinity DataIC50: 660nMAssay Description:Inhibition of rat brain farnesyltransferase in 50 mM HEPES bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed