BDBM50055714 3-(4,7-dihydroxy-2-oxo-2H-3-chromenylmethyl)-4,7-dihydroxy-2H-2-chromenone::CHEMBL238291::CHEMBL312727

SMILES Oc1ccc2c(O)c(Cc3c(O)c4ccc(O)cc4oc3=O)c(=O)oc2c1

InChI Key InChIKey=ZCRYILRCCBOILO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50055714   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50055714(3-(4,7-dihydroxy-2-oxo-2H-3-chromenylmethyl)-4,7-d...)
Affinity DataIC50:  4.63E+4nMAssay Description:Inhibitory activity against 3'-processing of DNA by HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50055714(3-(4,7-dihydroxy-2-oxo-2H-3-chromenylmethyl)-4,7-d...)
Affinity DataIC50:  4.49E+4nMAssay Description:Integration of DNA by HIV -1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50055714(3-(4,7-dihydroxy-2-oxo-2H-3-chromenylmethyl)-4,7-d...)
Affinity DataIC50:  2.23E+7nMAssay Description:Inhibition of Human immunodeficiency virus 1 integraseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50055714(3-(4,7-dihydroxy-2-oxo-2H-3-chromenylmethyl)-4,7-d...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human recombinant NQO1 in presence of BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50055714(3-(4,7-dihydroxy-2-oxo-2H-3-chromenylmethyl)-4,7-d...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed