BDBM50056029 CHEMBL316960::N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-2,6-dimethyl-piperazin-1-yl]-ethyl}-4-fluoro-benzamide

SMILES CC1CN(CC(C)N1CCNC(=O)c1ccc(F)cc1)c1cccc2OCCOc12

InChI Key InChIKey=BRMLYAYOHYSGPN-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50056029   

Target5-hydroxytryptamine receptor 1A(Human)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50056029(N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-2,6-di...)
Affinity DataEC50:  0.780nMAssay Description:In vitro potency at human 5-hydroxytryptamine 1A receptor in inhibiting forskolin-stimulated accumulation of intracellular cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50056029(N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-2,6-di...)
Affinity DataKi:  1nMAssay Description:Binding affinity was evaluated by determining in vitro displacement of [3H]8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition sit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed