BDBM50056239 6-[(4,5-Dimethoxy-2-pyrrol-1-yl-phenylamino)-methyl]-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL356722

SMILES COc1cc(NCc2cnc3nc(N)nc(N)c3c2C)c(cc1OC)-n1cccc1

InChI Key InChIKey=ILPSSJNFDZTGRW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056239   

TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056239(6-[(4,5-Dimethoxy-2-pyrrol-1-yl-phenylamino)-methy...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056239(6-[(4,5-Dimethoxy-2-pyrrol-1-yl-phenylamino)-methy...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056239(6-[(4,5-Dimethoxy-2-pyrrol-1-yl-phenylamino)-methy...)
Affinity DataIC50:  600nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed