BDBM50056393 4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-phenyl-piperazin-1-yl)-ethyl ester::CHEMBL123377

SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(CC1)c1ccccc1

InChI Key InChIKey=NILZUNSWBMWMBN-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50056393   

Target5-hydroxytryptamine receptor 4(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50056393(4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pheny...)
Affinity DataKi:  12.5nMAssay Description:Binding affinity was determined against cloned 5-hydroxytryptamine 4C receptor isoform expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50056393(4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pheny...)
Affinity DataKi:  14.3nMAssay Description:Binding affinity was determined against cloned 5-hydroxytryptamine 4E receptor isoform expressed in C6 glial cells incubated with 0.2 nM [3H]GR-11380...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50056393(4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pheny...)
Affinity DataKi:  23nMAssay Description:Binding affinity was determined against cloned 5-hydroxytryptamine 4A receptor isoform expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50056393(4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pheny...)
Affinity DataKi:  32nMAssay Description:Binding affinity was determined against cloned 5-hydroxytryptamine 4D receptor isoform expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50056393(4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pheny...)
Affinity DataKi:  55nMAssay Description:Binding affinity was determined against cloned 5-hydroxytryptamine 4B receptor isoform expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50056393(4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pheny...)
Affinity DataIC50: 100nMAssay Description:5-hydroxytryptamine 4 receptor antagonist activity, concentration which gave 50% reduction of the 5-HT-induced contractions in the guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed