BDBM50056554 1-(2-Benzhydryloxy-ethyl)-4-(3-thiophen-2-yl-propyl)-piperazine::CHEMBL164207

SMILES C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1cccs1

InChI Key InChIKey=LZIOWZFBJQHWNY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056554   

TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50056554(1-(2-Benzhydryloxy-ethyl)-4-(3-thiophen-2-yl-propy...)
Affinity DataIC50: 5.20nMAssay Description:Binding affinity at the dopamine transporter using [125I]RTI-55 in rat caudate membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50056554(1-(2-Benzhydryloxy-ethyl)-4-(3-thiophen-2-yl-propy...)
Affinity DataIC50: 9.70nMAssay Description:Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]dopamine on synaptosomes obtained from rat caudate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50056554(1-(2-Benzhydryloxy-ethyl)-4-(3-thiophen-2-yl-propy...)
Affinity DataIC50: 842nMAssay Description:Binding affinity at the serotonin transporter using [125I]RTI-55 in rat caudate membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50056554(1-(2-Benzhydryloxy-ethyl)-4-(3-thiophen-2-yl-propy...)
Affinity DataIC50: 1.99E+3nMAssay Description:Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-5-HT on synaptosomes obtained from whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed