BDBM50056822 4-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylazo)-N-(5-methyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide::CHEMBL127388

SMILES Cc1nnc(NS(=O)(=O)c2ccc(cc2)N=Nc2c(C)[nH]n(-c3ccccc3)c2=O)s1

InChI Key InChIKey=XTMXZTUIBZRILJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056822   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056822(4-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-...)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibitory concentration against HIV-1 integrase by strand transfer methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056822(4-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-...)
Affinity DataIC50: 7.76E+4nMAssay Description:Inhibitory activity against DNA strand transfer by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056822(4-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-...)
Affinity DataIC50: 1.34E+5nMAssay Description:Inhibitory concentration to inhibit HIV-1 integrase by 3' -processing methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056822(4-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-...)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibitory activity against 3' processing by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed