BDBM50056827 4-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylazo)-N-(4-methyl-pyrimidin-2-yl)-benzenesulfonamide::CHEMBL338145

SMILES Cc1[nH]n(-c2ccccc2)c(=O)c1N=Nc1ccc(cc1)S(=O)(=O)Nc1nccc(C)n1

InChI Key InChIKey=QSRAFNHRUIQRPQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056827   

TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056827(4-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-...)
Affinity DataIC50: 2.34E+4nMAssay Description:Inhibitory activity against DNA strand transfer by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056827(4-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-...)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibitory concentration against HIV-1 integrase by strand transfer methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056827(4-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibitory activity against 3' processing by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056827(4-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibitory concentration to inhibit HIV-1 integrase by 3' -processing methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed