BDBM50056849 4-(3-Acetyl-2-oxo-tetrahydro-furan-3-ylazo)-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL129055

SMILES CC(=O)C1(CCOC1=O)N=Nc1ccc(cc1)S(=O)(=O)Nc1onc(C)c1C

InChI Key InChIKey=VOUJPBIIZGLQJV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056849   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056849(4-(3-Acetyl-2-oxo-tetrahydro-furan-3-ylazo)-N-(3,4...)
Affinity DataIC50: 1.43E+5nMAssay Description:Inhibitory concentration against HIV-1 integrase by strand transfer methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056849(4-(3-Acetyl-2-oxo-tetrahydro-furan-3-ylazo)-N-(3,4...)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibitory activity against DNA strand transfer by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056849(4-(3-Acetyl-2-oxo-tetrahydro-furan-3-ylazo)-N-(3,4...)
Affinity DataIC50: 1.93E+5nMAssay Description:Inhibitory concentration to inhibit HIV-1 integrase by 3' -processing methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056849(4-(3-Acetyl-2-oxo-tetrahydro-furan-3-ylazo)-N-(3,4...)
Affinity DataIC50: 1.95E+5nMAssay Description:Inhibitory activity against 3' processing by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed