BDBM50056867 4-(3-Acetyl-2-oxo-tetrahydro-furan-3-ylazo)-N-(5-methyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide::CHEMBL341067

SMILES CC(=O)C1(CCOC1=O)N=Nc1ccc(cc1)S(=O)(=O)Nc1nnc(C)s1

InChI Key InChIKey=SEQHLNPJWFZWSM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50056867   

TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056867(4-(3-Acetyl-2-oxo-tetrahydro-furan-3-ylazo)-N-(5-m...)
Affinity DataIC50: 1.78E+5nMAssay Description:Inhibitory activity against DNA strand transfer by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50056867(4-(3-Acetyl-2-oxo-tetrahydro-furan-3-ylazo)-N-(5-m...)
Affinity DataIC50: 1.78E+5nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase strand transfer activity using [32P]5'end-labeled linear 21 mer as substrate incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056867(4-(3-Acetyl-2-oxo-tetrahydro-furan-3-ylazo)-N-(5-m...)
Affinity DataIC50: 1.78E+5nMAssay Description:Inhibitory concentration against HIV-1 integrase by strand transfer methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056867(4-(3-Acetyl-2-oxo-tetrahydro-furan-3-ylazo)-N-(5-m...)
Affinity DataIC50: 2.44E+5nMAssay Description:Inhibitory concentration to inhibit HIV-1 integrase by 3' -processing methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056867(4-(3-Acetyl-2-oxo-tetrahydro-furan-3-ylazo)-N-(5-m...)
Affinity DataIC50: 2.45E+5nMAssay Description:Inhibitory activity against 3' processing by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed