BDBM50056871 CHEMBL421441::N-(3,4-Dimethyl-thiophen-2-yl)-4-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylazo)-benzenesulfonamide

SMILES Cc1csc(NS(=O)(=O)c2ccc(cc2)N=Nc2c(C)[nH]n(-c3ccccc3)c2=O)c1C

InChI Key InChIKey=FPIBDEHNNPFARK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056871   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056871(N-(3,4-Dimethyl-thiophen-2-yl)-4-(3-methyl-5-oxo-1...)
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibitory concentration required to inhibit HIV-1 integrase by strand transfer methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056871(N-(3,4-Dimethyl-thiophen-2-yl)-4-(3-methyl-5-oxo-1...)
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibitory activity against DNA strand transfer by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056871(N-(3,4-Dimethyl-thiophen-2-yl)-4-(3-methyl-5-oxo-1...)
Affinity DataIC50: 1.24E+5nMAssay Description:Inhibitory concentration to inhibit HIV-1 integrase by 3' -processingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056871(N-(3,4-Dimethyl-thiophen-2-yl)-4-(3-methyl-5-oxo-1...)
Affinity DataIC50: 1.29E+5nMAssay Description:Inhibitory activity against 3' processing by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed