BDBM50057252 3-Chloro-4-hydroxy-5-{(E)-3-[4-(quinolin-2-ylmethoxy)-phenyl]-acryloyl}-benzoic acid::3-chloro-4-hydroxy-5-(3-(4-(quinolin-2-ylmethoxy)phenyl)acryloyl)benzoic acid::CHEMBL11785

SMILES OC(=O)c1cc(Cl)c(O)c(c1)C(=O)\C=C\c1ccc(OCc2ccc3ccccc3n2)cc1

InChI Key InChIKey=KRFOTWNULZGQIS-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057252   Sort by

TargetCysteinyl leukotriene receptor 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50057252(3-chloro-4-hydroxy-5-(3-(4-(quinolin-2-ylmethoxy)p...)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50057252(3-chloro-4-hydroxy-5-(3-(4-(quinolin-2-ylmethoxy)p...)
Affinity DataKd:  1.70E+3nMAssay Description:Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed