BDBM50057311 5-((3,4-dimethoxyphenylthio)methyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::5-(3,4-Dimethoxy-phenylsulfanylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::CHEMBL17431

SMILES COc1ccc(SCc2c[nH]c3nc(N)nc(N)c23)cc1OC

InChI Key InChIKey=GMMNRNFBCUQMFF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50057311   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057311(5-(3,4-Dimethoxy-phenylsulfanylmethyl)-7H-pyrrolo[...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057311(5-(3,4-Dimethoxy-phenylsulfanylmethyl)-7H-pyrrolo[...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057311(5-(3,4-Dimethoxy-phenylsulfanylmethyl)-7H-pyrrolo[...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057311(5-(3,4-Dimethoxy-phenylsulfanylmethyl)-7H-pyrrolo[...)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057311(5-(3,4-Dimethoxy-phenylsulfanylmethyl)-7H-pyrrolo[...)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057311(5-(3,4-Dimethoxy-phenylsulfanylmethyl)-7H-pyrrolo[...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057311(5-(3,4-Dimethoxy-phenylsulfanylmethyl)-7H-pyrrolo[...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057311(5-(3,4-Dimethoxy-phenylsulfanylmethyl)-7H-pyrrolo[...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed