BDBM50057315 5-(Naphthalen-1-ylsulfanylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::CHEMBL17479

SMILES Nc1nc(N)c2c(CSc3cccc4ccccc34)c[nH]c2n1

InChI Key InChIKey=RVDHJIXZPBMVLP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50057315   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057315(5-(Naphthalen-1-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 810nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057315(5-(Naphthalen-1-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 810nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057315(5-(Naphthalen-1-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057315(5-(Naphthalen-1-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057315(5-(Naphthalen-1-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057315(5-(Naphthalen-1-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed