BDBM50057316 5-(((2,5-dimethoxyphenyl)(methyl)amino)methyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::CHEMBL17453

SMILES COc1ccc(OC)c(c1)N(C)Cc1c[nH]c2nc(N)nc(N)c12

InChI Key InChIKey=JSLWFRFGAYXGRR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50057316   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057316(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-7...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057316(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-7...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057316(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-7...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057316(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-7...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057316(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-7...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed