BDBM50057318 5-(Naphthalen-2-ylsulfanylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::CHEMBL275893

SMILES Nc1nc(N)c2c(CSc3ccc4ccccc4c3)c[nH]c2n1

InChI Key InChIKey=GVERFKPFPDSBRD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50057318   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057318(5-(Naphthalen-2-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057318(5-(Naphthalen-2-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition against Dihydrofolate reductase in Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057318(5-(Naphthalen-2-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 8.29E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057318(5-(Naphthalen-2-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 8.29E+4nMAssay Description:Inhibition against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057318(5-(Naphthalen-2-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 9.29E+5nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50057318(5-(Naphthalen-2-ylsulfanylmethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 9.29E+5nMAssay Description:Inhibition against Dihydrofolate reductase in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed