BDBM50057448 (10R,13S,17S)-17-Diisopropylcarbamoyl-10,13-dimethyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3-carboxylic acid::17-Diisopropylcarbamoyl-10,13-dimethyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3-carboxylic acid::CHEMBL278283

SMILES CC(C)N(C(=O)[C@H]1CCC2C3CC=C4C=C(C(=O)O)CC[C@]4(C)C3CC[C@@]21C)C(C)C

InChI Key InChIKey=JDAULUKGZUDSNK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057448   

LigandChemical structure of BindingDB Monomer ID 50057448BDBM50057448(17-Diisopropylcarbamoyl-10,13-dimethyl-2,7,8,9,10,...)
Affinity DataKi:  7nMAssay Description:Compound was tested for inhibitory activity against human prostatic Steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50057448BDBM50057448(17-Diisopropylcarbamoyl-10,13-dimethyl-2,7,8,9,10,...)
Affinity DataKi:  7nMAssay Description:In vitro inhibitory activity against Steroid 5-alpha-reductase was determined in human prostatic tissue expressed as apparent inhibition constant; Ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50057448BDBM50057448(17-Diisopropylcarbamoyl-10,13-dimethyl-2,7,8,9,10,...)
Affinity DataKi:  35nMAssay Description:In vitro inhibitory activity against Steroid 5-alpha-reductase was determined in rat ventral prostates expressed as apparent inhibition constant; Ran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed