BDBM50057919 2-(3-Chloro-5-methyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole::CHEMBL295032

SMILES Cc1cc(Cl)cc(c1)-c1nc(cn1-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=LHCKWZHVMBWHKK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057919   

TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50057919(2-(3-Chloro-5-methyl-phenyl)-1-(4-methanesulfonyl-...)
Affinity DataIC50: 79.4nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50057919(2-(3-Chloro-5-methyl-phenyl)-1-(4-methanesulfonyl-...)
Affinity DataIC50: 80nMAssay Description:Concentration required to inhibit human Prostaglandin G/H synthase 2 (COX-2) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057919(2-(3-Chloro-5-methyl-phenyl)-1-(4-methanesulfonyl-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Concentration required to inhibit human prostaglandin G/H synthase 1 (COX-1) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed