BDBM50057932 2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4-methyl-1H-imidazole::CHEMBL46761

SMILES Cc1cn(c(n1)-c1ccc(Cl)cc1)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=RIZFWOPNUQFLEF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50057932   

TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057932(2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to inhibit human prostaglandin G/H synthase 1 (COX-1) by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057932(2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4...)
Affinity DataIC50:  240nMAssay Description:Concentration required to inhibit human Prostaglandin G/H synthase 2 (COX-2) by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 2(Mouse)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50057932(2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4...)
Affinity DataIC50:  2.39E+8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057932(2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 1(Sheep)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50057932(2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX1 using fluorometric substrate by fluorescent inhibitor screening assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed