BDBM50058089 3-{[3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amino}-benzoic acid; compound with acetic acid::CHEMBL47008

SMILES Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2cccc(c2)C(O)=O)c1Br

InChI Key InChIKey=PZCFZONZHSIXRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058089   

TargetEndothelin-1 receptor(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058089(3-{[3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-th...)
Affinity DataIC50: 62nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058089(3-{[3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-th...)
Affinity DataIC50: 1.17E+5nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed