BDBM50058102 3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (6-acetyl-benzo[1,3]dioxol-5-yl)-amide::CHEMBL295583

SMILES CC(=O)c1cc2OCOc2cc1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1C

InChI Key InChIKey=LTAJIUUAOOWVSJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058102   

TargetEndothelin-1 receptor(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058102(3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-...)
Affinity DataIC50: 31nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058102(3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed